Southern Indiana is a region shaped by its proximity to the Ohio River, rolling hills, and deep historical roots. This area differs geographically and culturally from northern parts of the state, featuring more varied terrain, scenic landscapes, and historic river towns.
Many cities in Southern Indiana developed around river trade, early settlement routes, and agriculture. These communities often feature historic downtowns, preserved architecture, and long-standing cultural traditions. While agriculture remains important, modern Southern Indiana also includes manufacturing, healthcare, tourism, and cross-border economic ties with Kentucky.
Outdoor recreation is a defining feature of the region, with parks, forests, trails, and waterways supporting tourism and local lifestyles. Cities in Southern Indiana tend to emphasize heritage, community events, and regional identity, offering a distinct and welcoming character within the broader context of the Hoosier State.
| City | Population | County |
|---|---|---|
| Attica | 3,100 | Fountain County |
| Aurora | 3,700 | Dearborn County |
| Batesville | 7,100 | Ripley County |
| Bedford | 13,800 | Lawrence County |
| Bloomington | 79,200 | Monroe County |
| Boonville | 6,300 | Warrick County |
| Brazil | 7,900 | Clay County |
| Brookville | 2,600 | Franklin County |
| Clarksville | 22,800 | Clark County |
| Clinton | 4,900 | Vermillion County |
| Columbus | 50,500 | Bartholomew County |
| Connersville | 13,000 | Fayette County |
| Corydon | 3,200 | Harrison County |
| Covington | 2,400 | Fountain County |
| Evansville | 117,300 | Vanderburgh County |
| Greensburg | 12,600 | Decatur County |
| Jasper | 16,700 | Dubois County |
| Jeffersonville | 50,100 | Clark County |
| Lawrenceburg | 5,200 | Dearborn County |
| Liberty | 2,100 | Union County |
| Ligonier | 4,400 | Noble County |
| Linton | 5,300 | Greene County |
| Logansport | 18,200 | Cass County |
| Madison | 11,000 | Jefferson County |
| Mount Vernon | 6,700 | Posey County |
| New Albany | 37,800 | Floyd County |
| New Harmony | 750 | Posey County |
| Newburgh | 3,300 | Warrick County |
| North Vernon | 6,700 | Jennings County |
| Paoli | 3,700 | Orange County |
| Princeton | 8,600 | Gibson County |
| Rensselaer | 6,100 | Jasper County |
| Richmond | 35,700 | Wayne County |
| Rising Sun | 2,200 | Ohio County |
| Rockville | 2,600 | Parke County |
| Salem | 6,500 | Washington County |
| Santa Claus | 2,600 | Spencer County |
| Scottsburg | 7,300 | Scott County |
| Seymour | 21,600 | Jackson County |
| South Haven | 5,100 | Porter County |
| Sullivan | 4,100 | Sullivan County |
| Tell City | 7,200 | Perry County |
| Terre Haute | 58,300 | Vigo County |
| Union City | 3,400 | Randolph County |
| Versailles | 2,100 | Ripley County |
| Vevay | 1,700 | Switzerland County |
| Vincennes | 16,600 | Knox County |
| Washington | 12,000 | Daviess County |
| Winchester | 4,900 | Randolph County |
| Wolcott | 1,000 | White County |